Medical illustration for Based on PubMed | Is it true that eating Brazil nuts can improve thyroid function in people with Hashimoto's thyroiditis because of their selenium content? - Persly Health Information
Persly Medical TeamPersly Medical Team
February 18, 20265 min read

Based on PubMed | Is it true that eating Brazil nuts can improve thyroid function in people with Hashimoto's thyroiditis because of their selenium content?

Key Takeaway:

Brazil nuts can help meet selenium needs, and selenium may reduce thyroid antibodies in some people with Hashimoto’s. However, evidence that this improves thyroid hormone levels, symptoms, or medication requirements is inconsistent. Because selenium content in Brazil nuts varies widely and excess can be harmful, keep portions small and discuss with your clinician.

Eating Brazil nuts may help some people with Hashimoto’s get enough selenium, but evidence that this reliably “improves thyroid function” is limited and mixed. Small trials suggest selenium can lower thyroid antibody levels (especially TPO antibodies), but consistent improvements in symptoms, thyroid hormone levels, or medication needs have not been clearly proven. [1] [2] [3] [4] [5]

What selenium does for the thyroid

  • Selenium is essential for enzymes that activate and deactivate thyroid hormones and for antioxidant defenses in thyroid tissue. Getting adequate selenium supports normal thyroid physiology, but “more” is not necessarily “better.” [6] [7]
  • In Hashimoto’s thyroiditis, some randomized studies show that selenium 200 µg/day (often as selenomethionine) can reduce anti–thyroid peroxidase (TPO) antibody levels; however, the overall quality of evidence is low to moderate and outcomes important to daily life like quality of life, levothyroxine dose, or long‑term thyroid function have not shown consistent benefit. Systematic review authors concluded the evidence is incomplete and not strong enough to recommend routine selenium for all people with Hashimoto’s. [1] [2] [3] [4] [5]

Brazil nuts as a selenium source

  • Brazil nuts are naturally very rich in selenium and can help meet daily needs. However, selenium content varies widely by growing region and even between individual nuts ranging from very low to extremely high making dosage unpredictable. [8] [9] [10]
  • Typical dietary recommendations for selenium in adults are about 55 µg/day, with a tolerable upper intake level of 400 µg/day to avoid toxicity. Because some Brazil nuts can contain several hundred micrograms of selenium each, eating multiple nuts daily could exceed the safe upper limit. [11] [12] [6] [13]

Safety and toxicity considerations

  • Chronic excess selenium (selenosis) can cause hair and nail changes, gastrointestinal upset, fatigue, irritability, and mild nerve problems. Severe overdose can lead to serious systemic toxicity; while rare, it underscores the importance of not exceeding the upper limit (400 µg/day). [12] [6] [13]
  • Some observational and experimental data suggest potential risks from long‑term high selenium exposure at relatively modest intakes, including possible effects on glucose metabolism, though findings are not uniform. Practical takeaway: aim for adequacy, avoid excess. [14]

What guidelines and experts generally suggest

  • For hypothyroidism due to Hashimoto’s, the foundation of care is appropriate levothyroxine dosing when indicated. Dietary factors including adequate but not excessive iodine and selenium support thyroid health, but they do not replace thyroid hormone therapy when needed. [15] [16] [17]
  • Routine selenium supplementation for all individuals with Hashimoto’s is not firmly recommended because of limited, inconsistent outcome data. If supplementation is considered, it’s typically short‑term and monitored, balancing potential antibody reductions against uncertain clinical benefit and the risk of excess. [1] [2] [3] [4] [5]

Practical advice if you’re considering Brazil nuts

  • If you want to use diet instead of pills, Brazil nuts can be a reasonable option to cover selenium needs, provided intake is modest. Because a single nut may contain anywhere from tens to several hundred micrograms, many clinicians suggest limiting to about 1 Brazil nut per day (or even 2–3 per week) to avoid exceeding the upper limit. [8] [9] [10] [13]
  • If you prefer the consistency of a supplement, discuss a standardized dose (often 50–100 µg/day if your diet is low) with your clinician and avoid doses that could push your total intake near 400 µg/day. Your total selenium includes food, fortified products, and supplements consider all sources. [11] [13]
  • Continue standard thyroid management and monitoring. Changes in symptoms and thyroid labs (TSH, free T4) matter more than antibody numbers alone when judging clinical benefit. [15] [16]

Quick reference: selenium and Brazil nuts

TopicKey points
Evidence in Hashimoto’sAntibody reductions seen with 200 µg/day in some trials; clinical benefits (symptoms, levothyroxine dose, thyroid function) remain uncertain. [1] [2] [3] [4] [5]
Adult selenium needsRecommended intake ~55 µg/day; do not exceed 400 µg/day (tolerable upper limit). [11] [13]
Brazil nut variabilitySelenium per nut varies dramatically by region and nut; dose is unpredictable. [8] [9] [10]
ToxicityExcess can cause hair/nail changes, GI upset, fatigue, irritability, neuropathy; severe cases have occurred with very high intakes. [12] [6]
Core treatmentAppropriate levothyroxine and medication timing/absorption remain central; diet is supportive. [15] [16]

Bottom line

  • It’s reasonable to say that getting enough selenium through food or carefully dosed supplements supports normal thyroid processes, and some people with Hashimoto’s may see reductions in thyroid antibodies. But the current evidence does not clearly show that selenium (or Brazil nuts specifically) consistently improves thyroid hormone levels, symptoms, or medication requirements. [1] [2] [3] [4] [5]
  • If you enjoy Brazil nuts, a small amount can help meet selenium needs, but because of highly variable selenium content, stick to very modest portions (often ~1 nut/day or a few per week) and avoid exceeding the safe upper limit especially if you also take a multivitamin containing selenium. [8] [9] [10] [13] [11]

As always, coordinate any supplementation or dietary strategy with your clinician and continue routine thyroid monitoring to track what truly matters your symptoms and thyroid hormone levels. [15] [16]

Related Questions

Related Articles

Sources

  1. 1.^abcdeSelenium supplementation for Hashimoto's thyroiditis.(pubmed.ncbi.nlm.nih.gov)
  2. 2.^abcdeSelenium supplementation for Hashimoto's thyroiditis.(pubmed.ncbi.nlm.nih.gov)
  3. 3.^abcdeSelenium supplementation for Hashimoto's thyroiditis.(pubmed.ncbi.nlm.nih.gov)
  4. 4.^abcdeSelenium supplementation for Hashimoto's thyroiditis.(pubmed.ncbi.nlm.nih.gov)
  5. 5.^abcdeSelenium supplementation for Hashimoto's thyroiditis.(pubmed.ncbi.nlm.nih.gov)
  6. 6.^abcdSelenium(mskcc.org)
  7. 7.^Selenium(mskcc.org)
  8. 8.^abcdSelenium content of Brazil nuts from two geographic locations in Brazil.(pubmed.ncbi.nlm.nih.gov)
  9. 9.^abcdSelenium content of Brazil nuts from two geographic locations in Brazil.(pubmed.ncbi.nlm.nih.gov)
  10. 10.^abcdSelenium content of Brazil nuts from two geographic locations in Brazil.(pubmed.ncbi.nlm.nih.gov)
  11. 11.^abcdSelenium in diet: MedlinePlus Medical Encyclopedia(medlineplus.gov)
  12. 12.^abcSelenium in diet: MedlinePlus Medical Encyclopedia(medlineplus.gov)
  13. 13.^abcdefSelenium(mskcc.org)
  14. 14.^Risk of chronic low-dose selenium overexposure in humans: insights from epidemiology and biochemistry.(pubmed.ncbi.nlm.nih.gov)
  15. 15.^abcdCan certain foods improve thyroid function in people with hypothyroidism?(mayoclinic.org)
  16. 16.^abcdCan certain foods improve thyroid function in people with hypothyroidism?(mayoclinic.org)
  17. 17.^Can certain foods improve thyroid function in people with hypothyroidism?(mayoclinic.org)

Important Notice: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before making any medical decisions.