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Persly Medical TeamPersly Medical Team
January 26, 20265 min read

Is Hearing Loss Linked to Prostate Cancer?

Key Takeaway:

Is hearing loss a common symptom of Prostate Cancer?

Hearing loss is not considered a common or typical symptom of prostate cancer itself. Most prostate cancer symptoms involve urinary changes, fatigue, bone pain, or weight loss, rather than ear or hearing problems. [1] Hearing loss associated with prostate cancer more commonly arises from certain treatments (especially specific chemotherapies) or unrelated ear conditions. [2] [3]


What typically causes hearing loss in this context?

  • Cancer treatments (ototoxic medications): Some chemotherapy drugs most notably platinum agents like cisplatin can injure the inner ear, leading to tinnitus (ringing) and sensorineural hearing loss. This risk is recognized across oncology guidance, and patients are advised to be monitored for symptoms and with audiometry when indicated. [4] [5]

    • While cisplatin is not a standard first‑line drug for prostate cancer, platinum agents may be used in select advanced or refractory cases, and the ototoxicity profile still applies. [6]
  • Other medications: High doses of certain non‑cancer drugs (such as aspirin, loop diuretics, some antimalarials) can cause temporary tinnitus or hearing loss; this can complicate hearing during cancer care if these medicines are being taken. [3]

  • Radiation and nerve damage (less common): Head and neck radiation can affect hearing, but prostate radiation does not target ear structures and isn’t expected to cause hearing loss. [2]

    • Very rarely, paraneoplastic neurological syndromes can occur in cancer, but these syndromes most often affect balance, movement, or cognition rather than causing isolated hearing loss. [7] [8]
  • Unrelated ear conditions: Age‑related hearing loss, noise exposure, ear infections, and other medical illnesses (for example, meningitis) can harm the cochlea and cause hearing problems independent of prostate cancer. These are among the most common reasons people experience hearing changes. [3]


How to tell if hearing loss is treatment‑related vs. unrelated

  • Timing: Hearing changes starting soon after receiving an ototoxic drug (e.g., cisplatin) are more suggestive of treatment‑related effects. Guidelines recommend symptom monitoring and audiometry if tinnitus or hearing changes develop during platinum therapy. [4] [5]
  • Dose and exposure: Cumulative doses of ototoxic medications increase risk; concurrent nephrotoxic/ototoxic drugs (e.g., aminoglycosides) can make ototoxicity worse. [4] [5]
  • Location of cancer care: Prostate‑directed radiation or hormone therapy generally doesn’t target the ear, so hearing loss during these treatments often points to other causes. [2] [9]

Management: practical steps

  • Report symptoms early: If you notice tinnitus or hearing changes during cancer treatment, let your oncology team know promptly and ask about an audiometry test. [4] [5]

  • Medication review: Work with your clinicians to identify and reduce exposure to ototoxic drugs when safe to do so, including non‑cancer medications like high‑dose aspirin or certain diuretics. [3]

  • Adjust cancer therapy when possible: For regimens that include ototoxic agents, dose adjustments, schedule changes, or switching drugs may be considered to balance cancer control and hearing preservation. [4] [5]

  • Hearing support:

    • Hearing aids and assistive listening devices can improve communication and quality of life when inner ear damage exists. Specialty care focuses on getting sound signals to the brain and treating any underlying contributors. [10]
    • Tinnitus strategies (sound therapy, stress reduction, sleep hygiene) can help with ringing sensations, which often accompany treatment‑related hearing changes. [3]
  • Protect the ears: Avoid loud noise exposure and use hearing protection during and after treatment to reduce additional inner ear strain. [3]

  • Monitor over time: Because ototoxic effects can be delayed or cumulative, periodic hearing checks may be useful if you’ve received a known ototoxic agent. [4] [5]


When to seek medical evaluation

  • New or worsening hearing loss or persistent tinnitus during or after cancer therapy warrants evaluation by oncology and audiology. Early testing can document baseline and change, guiding treatment decisions. [4] [5]
  • Sudden hearing loss (over hours to days) should be treated as urgent; rapid assessment is important because some causes respond best to timely therapy. [3]

Key takeaways

  • Hearing loss is not a typical symptom of prostate cancer itself. [1]
  • Treatment‑related ototoxicity especially from platinum chemotherapy can cause hearing changes, and monitoring is advised. [4] [5]
  • Most hearing issues have non‑cancer causes such as age‑related change or noise exposure, so a comprehensive evaluation is important. [3]
  • Management includes early reporting, medication review, audiometry, hearing support, and ear protection. [10] [3]

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Related Questions

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Sources

  1. 1.^abProstate cancer - Symptoms and causes(mayoclinic.org)
  2. 2.^abcProstate cancer - Diagnosis and treatment(mayoclinic.org)
  3. 3.^abcdefghiHearing loss - Symptoms and causes(mayoclinic.org)
  4. 4.^abcdefgh229-Mesothelioma ciSplatin and pemetrexed | eviQ(eviq.org.au)
  5. 5.^abcdefgh4316-NSCLC neoadjuvant ciSplatin gemcitabine and nivolumab(eviq.org.au)
  6. 6.^Treatments(stanfordhealthcare.org)
  7. 7.^Paraneoplastic syndromes of the nervous system - Symptoms and causes(mayoclinic.org)
  8. 8.^Paraneoplastic syndromes of the nervous system - Symptoms and causes(mayoclinic.org)
  9. 9.^Hormone Therapies & Other Systemic Therapies for Prostate Cancer(nyulangone.org)
  10. 10.^abLiver Cancer Treatments(stanfordhealthcare.org)

Important Notice: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before making any medical decisions.