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Persly Medical TeamPersly Medical Team
January 26, 20265 min read

Is hearing loss linked to lung cancer?

Key Takeaway:

Is hearing loss a common symptom of lung cancer?

Hearing loss is not a common symptom of lung cancer itself, and typical signs are respiratory and systemic (cough, chest pain, shortness of breath, hoarseness, weight loss). [1] Many recognized symptom lists for lung cancer do not include hearing loss among core presentations. [2] When hearing problems occur in someone with lung cancer, they are usually due to treatments (ototoxic chemotherapy), brain spread of cancer, or other medical causes rather than the lung tumor directly. [3]


Typical lung cancer symptoms

  • Respiratory symptoms such as persistent cough, coughing up blood, wheezing, and shortness of breath are common. [1]
  • Voice hoarseness and chest pain can appear, along with repeated infections. [2]
  • Systemic signs like unintended weight loss, fatigue, and appetite loss may occur as the disease advances or spreads. [1] [2]

These help distinguish lung cancer’s usual presentation from ear-related issues like hearing loss. [1] [2]


Why hearing loss can occur in people with lung cancer

1) Treatment-related ototoxicity (ear toxicity)

  • Cisplatin and other platinum chemotherapy can damage the inner ear, causing tinnitus (ringing) and sensorineural hearing loss; tinnitus is often reversible, but hearing loss is commonly irreversible and dose-related. [4]
  • Ototoxicity risk increases with cumulative dosing and pre‑existing hearing problems; monitoring for symptoms is recommended, with audiometry if changes develop. [5]
  • Patient information for common lung cancer regimens warns of ringing or hearing loss and suggests hearing tests before and during treatment. [6] [7]
  • Evidence reviews note a 5‑fold higher risk of hearing impairment with cisplatin, with many adults and children affected, and highlight the lack of standardized monitoring guidelines in routine practice. [PM13]
  • Clinical resources advise caution when combining ototoxic agents (for example, with some antibiotics like aminoglycosides), and recommend prompt evaluation if symptoms appear. [8] [9]

2) Brain metastases (spread to the brain)

  • Lung cancer can spread to the brain, where tumors can cause neurologic symptoms such as headaches, seizures, confusion, visual changes, speech trouble, weakness, or balance loss; auditory pathway involvement can contribute to hearing changes, though this is less typical. [10]

3) Paraneoplastic or other medical causes

  • Rare paraneoplastic neurologic syndromes linked to lung cancer can affect the nervous system without direct tumor spread; while hearing loss is not a hallmark, neurologic complaints should prompt evaluation. [11] [12]
  • Non‑cancer causes like age‑related hearing loss, infections (e.g., meningitis), loud noise exposure, or certain medications can also lead to hearing problems and may coexist during cancer care. [3]

Red flags that need urgent attention

  • Sudden hearing loss, new severe tinnitus, or rapid worsening hearing during or after chemotherapy should be reported immediately; dedicated guidance recommends audiometry if symptoms develop. [5] [8]
  • New neurologic symptoms (severe headache, seizures, confusion, weakness, balance problems, vision or speech changes) raise concern for brain spread and require urgent assessment. [10]

How hearing loss is evaluated

  • Symptom review and medication history (including chemotherapy cycles and other drugs with ototoxic potential). [8] [9]
  • Ear exam and audiology testing (audiogram) to document type and severity of loss. [5]
  • Blood tests and imaging if neurologic symptoms suggest brain involvement (brain MRI or CT). [10]
  • Consider baseline hearing tests before platinum chemotherapy and periodic monitoring in higher‑risk patients, as many clinical resources advise. [6] [5] [8]

Management options

If due to chemotherapy (ototoxicity)

  • Report symptoms early; dosing adjustments or switching regimens may be considered case‑by‑case. [8] [9]
  • Avoid other ototoxic medications when possible (for example, some aminoglycoside antibiotics). [8]
  • Audiology support: hearing aids, sound therapy for tinnitus, and communication strategies can improve daily functioning. [8]
  • Monitoring: ongoing hearing tests to track changes and guide treatment decisions. [5]

If due to brain metastases

  • Oncologic treatments (steroids to reduce swelling, radiation therapy, surgery, or systemic therapy) depend on number, size, and location of metastases. [10]
  • Neurologic rehabilitation and supportive care to address symptoms and preserve quality of life. [10]

If due to other causes

  • Manage middle/inner ear diseases, adjust non‑cancer medications that affect hearing, and apply standard treatments for age‑related hearing loss. [3]

Practical tips for preserving hearing during lung cancer care

  • 📋 Get baseline hearing testing if you will receive cisplatin or other known ototoxic drugs. [6] [5]
  • 🎧 Protect your ears from loud noises and limit exposure during treatment. [3]
  • 💊 Share all medications (including over‑the‑counter pain relievers and antibiotics) with your care team to screen for ototoxic combinations. [8]
  • 🔔 Report new tinnitus or hearing changes promptly; early action may prevent further loss. [5] [8]
  • 🧠 Seek urgent care if hearing issues come with neurologic symptoms (headache, seizures, confusion, weakness). [10]

Quick comparison: common vs. ear-related issues

FeatureCommon in lung cancerLinked to hearing loss
Persistent cough, chest pain, blood in sputumYesNo direct link. [1]
Hoarseness, wheezing, shortness of breathYesNot primarily ear‑related. [1] [2]
Weight loss, appetite loss, fatigueYesSystemic, not ear‑specific. [1] [2]
Tinnitus or hearing loss during chemotherapyNo (cancer itself)Often treatment‑related (cisplatin). [6] [4] [5] [PM13]
Sudden neurologic symptomsVariableConsider brain metastases. [10]

Bottom line

  • Hearing loss is uncommon as a direct symptom of lung cancer, but it can arise during treatment especially with cisplatin or less commonly from brain metastases or other medical conditions. [1] [2] [4] [10] [3]
  • Early reporting and audiology monitoring are key, and management may include chemotherapy adjustments, hearing support, and evaluation for neurologic causes when indicated. [5] [8] [10]

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Sources

  1. 1.^abcdefghLung cancer - Symptoms and causes(mayoclinic.org)
  2. 2.^abcdefgLung Cancer(medlineplus.gov)
  3. 3.^abcdeHearing loss - Symptoms and causes(mayoclinic.org)
  4. 4.^abc3802-NSCLC adjuvant ciSplatin and pemetrexed(eviq.org.au)
  5. 5.^abcdefghi3802-NSCLC adjuvant ciSplatin and pemetrexed(eviq.org.au)
  6. 6.^abcdPatient information - Lung cancer neoadjuvant - Cisplatin gemcitabine and nivolumab(eviq.org.au)
  7. 7.^Patient information - Lung cancer extensive disease - Cisplatin and irinotecan(eviq.org.au)
  8. 8.^abcdefghij1810-Ototoxicity | eviQ(eviq.org.au)
  9. 9.^abc3802-NSCLC adjuvant ciSplatin and pemetrexed(eviq.org.au)
  10. 10.^abcdefghiBrain metastases - Symptoms and causes(mayoclinic.org)
  11. 11.^Paraneoplastic syndromes of the nervous system - Symptoms and causes(mayoclinic.org)
  12. 12.^Paraneoplastic syndromes of the nervous system - Symptoms and causes(mayoclinic.org)

Important Notice: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before making any medical decisions.